Leptodactylus mystaceus is a species of frog in the family Leptodactylidae. It is also known as the common toad-frog.
It is found in northern South America. Its natural habitats are subtropical or tropical moist lowland forests, moist savanna, subtropical or tropical seasonally wet or flooded lowland grassland, intermittent freshwater marshes, pastureland, and heavily degraded former forest. It is not considered threatened by the IUCN.