Ramsden's least gecko (Sphaerodactylus ramsdeni ) is a species of lizard in the family Sphaerodactylidae. The species is endemic to Cuba.
The specific name, ramsdeni, is in honor of herpetologist Charles Theodore Ramsden (1876–1951), who collected the holotype in 1914.
S. ramsdeni has a very large rostral which is bordered posteriorly by six scales. The scales between the orbits are smooth. The dorsal scales are small. The ventrals are smooth. The posterior margin of each caudal is convex.
S. ramsdeni is oviparous.